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First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid

Paracetamol is arguably the most commonly used analgesic and antipyretic drug worldwide, however its mechanism of action is still not fully established. It has been shown to exert effects through multiple pathways, some actions suggested to be mediated via N-arachidonoylphenolamine (AM404). AM404, f...

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Detalles Bibliográficos
Autores principales: Sharma, Chhaya V, Long, Jamie H, Shah, Seema, Rahman, Junia, Perrett, David, Ayoub, Samir S, Mehta, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716395/
https://www.ncbi.nlm.nih.gov/pubmed/29238213
http://dx.doi.org/10.2147/JPR.S143500