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Isoliquiritigenin suppresses IL-1β induced apoptosis and inflammation in chondrocyte-like ATDC5 cells by inhibiting NF-κB and exerts chondroprotective effects on a mouse model of anterior cruciate ligament transection

Isoliquiritigenin (ISL), a natural flavonoid extracted from licorice, has been demonstrated to exert attenuation of the nuclear factor-κB (NF-κB) signaling pathway and anti-inflammatory activity in a wide variety of cells. In the present study, the authors first evaluated the effects of ISL on carti...

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Detalles Bibliográficos
Autores principales: Ji, Baochao, Guo, Wentao, Ma, Hairong, Xu, Boyong, Mu, Wenbo, Zhang, Zhendong, Amat, Abdusami, Cao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716454/
https://www.ncbi.nlm.nih.gov/pubmed/29039445
http://dx.doi.org/10.3892/ijmm.2017.3177