Cargando…

Monodisperse measurement of the biotin-streptavidin interaction strength in a well-defined pulling geometry

The widely used interaction of the homotetramer streptavidin with the small molecule biotin has been intensively studied by force spectroscopy and has become a model system for receptor ligand interaction. However, streptavidin’s tetravalency results in diverse force propagation pathways through the...

Descripción completa

Detalles Bibliográficos
Autores principales: Sedlak, Steffen M., Bauer, Magnus S., Kluger, Carleen, Schendel, Leonard C., Milles, Lukas F., Pippig, Diana A., Gaub, Hermann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716544/
https://www.ncbi.nlm.nih.gov/pubmed/29206886
http://dx.doi.org/10.1371/journal.pone.0188722