UNC-16/JIP3 regulates early events in synaptic vesicle protein trafficking via LRK-1/LRRK2 and AP complexes

JIP3/UNC-16/dSYD is a MAPK-scaffolding protein with roles in protein trafficking. We show that it is present on the Golgi and is necessary for the polarized distribution of synaptic vesicle proteins (SVPs) and dendritic proteins in neurons. UNC-16 excludes Golgi enzymes from SVP transport carriers a...

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Detalles Bibliográficos
Autores principales: Choudhary, Bikash, Kamak, Madhushree, Ratnakaran, Neena, Kumar, Jitendra, Awasthi, Anjali, Li, Chun, Nguyen, Ken, Matsumoto, Kunihiro, Hisamoto, Naoki, Koushika, Sandhya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716593/
https://www.ncbi.nlm.nih.gov/pubmed/29145394
http://dx.doi.org/10.1371/journal.pgen.1007100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716593/
https://www.ncbi.nlm.nih.gov/pubmed/29145394
http://dx.doi.org/10.1371/journal.pgen.1007100

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