Cargando…
UNC-16/JIP3 regulates early events in synaptic vesicle protein trafficking via LRK-1/LRRK2 and AP complexes
JIP3/UNC-16/dSYD is a MAPK-scaffolding protein with roles in protein trafficking. We show that it is present on the Golgi and is necessary for the polarized distribution of synaptic vesicle proteins (SVPs) and dendritic proteins in neurons. UNC-16 excludes Golgi enzymes from SVP transport carriers a...
Autores principales: | Choudhary, Bikash, Kamak, Madhushree, Ratnakaran, Neena, Kumar, Jitendra, Awasthi, Anjali, Li, Chun, Nguyen, Ken, Matsumoto, Kunihiro, Hisamoto, Naoki, Koushika, Sandhya P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716593/ https://www.ncbi.nlm.nih.gov/pubmed/29145394 http://dx.doi.org/10.1371/journal.pgen.1007100 |
Ejemplares similares
-
Active zone protein SYD-2/Liprin-α acts downstream of LRK-1/LRRK2 to regulate polarized trafficking of synaptic vesicle precursors through clathrin adaptor protein complexes
por: Nadiminti, Sravanthi S P, et al.
Publicado: (2023) -
UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport
por: Sure, Guruprasada Reddy, et al.
Publicado: (2018) -
Neurodegeneration and microtubule dynamics: death by a thousand cuts
por: Dubey, Jyoti, et al.
Publicado: (2015) -
Corrigendum: Neurodegeneration and microtubule dynamics: death by a thousand cuts
por: Dubey, Jyoti, et al.
Publicado: (2016) -
The Caenorhabditis elegans Kinesin-3 Motor UNC-104/KIF1A Is Degraded upon Loss of Specific Binding to Cargo
por: Kumar, Jitendra, et al.
Publicado: (2010)