Measurements of 6-thioguanine nucleotide levels with TPMT and NUDT15 genotyping in patients with Crohn’s disease

The association between the 6-thioguanine nucleotide (6-TGN) level and clinical remission in Crohn’s disease (CD) remains controversial. Thiopurine-induced leukopenia is a life-threatening complication of CD in Asians that was recently shown to strongly correlate with NUDT15 genetic variants. This s...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyeon, Kim, Tae Jun, Kim, Eun Ran, Hong, Sung Noh, Chang, Dong Kyung, Choi, Li-Hwa, Woo, Hye In, Lee, Soo-Youn, Kim, Young-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716599/
https://www.ncbi.nlm.nih.gov/pubmed/29206869
http://dx.doi.org/10.1371/journal.pone.0188925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716599/
https://www.ncbi.nlm.nih.gov/pubmed/29206869
http://dx.doi.org/10.1371/journal.pone.0188925

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