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Hedgehog signaling via Gli2 prevents obesity induced by high-fat diet in adult mice
Obesity poses a significant risk of developing type II diabetes and other diseases. Hedgehog (Hh) signaling has been shown to inhibit adipose tissue development, but its effect on diet-induced obesity during postnatal life is not known. Here by inducing expression of constitutively active Smoothened...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716664/ https://www.ncbi.nlm.nih.gov/pubmed/29205155 http://dx.doi.org/10.7554/eLife.31649 |