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Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height
GWAS have identified hundreds of height-associated loci. However, determining causal mechanisms is challenging, especially since height-relevant tissues (e.g. growth plates) are difficult to study. To uncover mechanisms by which height GWAS variants function, we performed epigenetic profiling of mur...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716665/ https://www.ncbi.nlm.nih.gov/pubmed/29205154 http://dx.doi.org/10.7554/eLife.29329 |