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Chromatin remodeling protein MORC2 promotes breast cancer invasion and metastasis through a PRD domain-mediated interaction with CTNND1

MORC family CW-type zinc finger 2 (MORC2) is a newly identified chromatin remodeling protein with emerging roles in the regulation of DNA damage response and gene transcription, but its mechanistic role in breast cancer development and progression remains unexplored. Here, we show that MORC2 promote...

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Detalles Bibliográficos
Autores principales: Liao, Xiao-Hong, Zhang, Ye, Dong, Wen-Jie, Shao, Zhi-Min, Li, Da-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716704/
https://www.ncbi.nlm.nih.gov/pubmed/29228664
http://dx.doi.org/10.18632/oncotarget.18556