Metformin ameliorates sepsis-induced brain injury by inhibiting apoptosis, oxidative stress and neuroinflammation via the PI3K/Akt signaling pathway

Sepsis-induced brain injuries increase mortality, morbidity, cognitive impairment and lack of effective therapeutic treatment. Previous studies have suggested that metformin provides neuroprotective effects against ischemia, brain trauma and other brain damage, but whether metformin protects a septi...

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Detalles Bibliográficos
Autores principales: Tang, Guangming, Yang, Huiyun, Chen, Jing, Shi, Mengrao, Ge, Lingqing, Ge, Xuhua, Zhu, Guoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716707/
https://www.ncbi.nlm.nih.gov/pubmed/29228667
http://dx.doi.org/10.18632/oncotarget.20105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716707/
https://www.ncbi.nlm.nih.gov/pubmed/29228667
http://dx.doi.org/10.18632/oncotarget.20105

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