Inhibition of pressure-activated cancer cell adhesion by FAK-derived peptides

Forces within the surgical milieu or circulation activate cancer cell adhesion and potentiate metastasis through signaling requiring FAK-Akt1 interaction. Impeding FAK-Akt1 interaction might inhibit perioperative tumor dissemination, facilitating curative cancer surgery without global FAK or AKT inh...

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Detalles Bibliográficos
Autores principales: Zeng, Bixi, Devadoss, Dinesh, Wang, Shouye, Vomhof-DeKrey, Emilie E., Kuhn, Leslie A., Basson, Marc D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716713/
https://www.ncbi.nlm.nih.gov/pubmed/29228673
http://dx.doi.org/10.18632/oncotarget.20556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716713/
https://www.ncbi.nlm.nih.gov/pubmed/29228673
http://dx.doi.org/10.18632/oncotarget.20556

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