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The regulatory role of aberrant Phosphatase and Tensin Homologue and Liver Kinase B1 on AKT/mTOR/c-Myc axis in pancreatic neuroendocrine tumors

Pancreatic neuroendocrine tumor (pNET) is an uncommon type of pancreatic neoplasm. Low Phosphatase and Tensin Homologue (PTEN) expression and activation of the mechanistic target of rapamycin (mTOR) pathway have been noted in pNETs, and the former is associated with poor survival in pNET patients. B...

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Detalles Bibliográficos
Autores principales: Chang, Tsung-Ming, Shan, Yan-Shen, Chu, Pei-Yi, Jiang, Shih Sheng, Hung, Wen-Chun, Chen, Yu-Lin, Tu, Hsiu-Chi, Lin, Hui-You, Tsai, Hui-Jen, Chen, Li-Tzong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716714/
https://www.ncbi.nlm.nih.gov/pubmed/29228674
http://dx.doi.org/10.18632/oncotarget.20956