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Cyclophosphamide causes osteoporosis in C57BL/6 male mice: suppressive effects of cyclophosphamide on osteoblastogenesis and osteoclastogenesis

The clinical evidence indicated that cyclophosphamide (CPD), one of the chemotherapy drugs, caused severe deteriorations in bones of cancer patients. However, the exact mechanisms by which CPD exerts effects on bone remodeling is not yet fully elucidated. Therefore, this study was performed to inves...

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Detalles Bibliográficos
Autores principales: Zhao, Dongfeng, Wang, Chenglong, Zhao, Yongjian, Shu, Bing, Jia, Youji, Liu, Shufen, Wang, Hongshen, Chang, Junli, Dai, Weiwei, Lu, Sheng, Shi, Qi, Yang, Yanping, Zhang, Yan, Wang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716721/
https://www.ncbi.nlm.nih.gov/pubmed/29228681
http://dx.doi.org/10.18632/oncotarget.21000