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Dl-3n-butylphthalide reduces epileptiform activity through GluA2-lacking calcium-permeable AMPARs in epilepsy models

Epilepsy is the most prevalent chronic neurological disorder, and its pathological mechanism indicates that an imbalance between excitatory and inhibitory neurotransmission leads to neuronal hyperexcitability. Previous studies have suggested that dl-3n-butylphthalide (NBP) regulates the excitatory n...

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Detalles Bibliográficos
Autores principales: Yang, Qin, Hu, Yi-Da, Wang, Xue-Feng, Zheng, Fang-Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716726/
https://www.ncbi.nlm.nih.gov/pubmed/29228686
http://dx.doi.org/10.18632/oncotarget.21529