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Iron depletion is a novel therapeutic strategy to target cancer stem cells

Adequate iron levels are essential for human health. However, iron overload can act as catalyst for the formation of free radicals, which may cause cancer. Cancer stem cells (CSCs), which maintain the hallmark stem cell characteristics of self-renewal and differentiation capacity, have been proposed...

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Detalles Bibliográficos
Autores principales: Ninomiya, Takayuki, Ohara, Toshiaki, Noma, Kazuhiro, Katsura, Yuki, Katsube, Ryoichi, Kashima, Hajime, Kato, Takuya, Tomono, Yasuko, Tazawa, Hiroshi, Kagawa, Shunsuke, Shirakawa, Yasuhiro, Kimura, Fumiaki, Chen, Ling, Kasai, Tomonari, Seno, Masaharu, Matsukawa, Akihiro, Fujiwara, Toshiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716739/
https://www.ncbi.nlm.nih.gov/pubmed/29228699
http://dx.doi.org/10.18632/oncotarget.21846