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Role of HIF-1a in regulating autophagic cell survival during cerebral ischemia reperfusion in rats

Hypoxia-inducible factor-1a (HIF-1a) plays a beneficial role during cerebral ischemia reperfusion (IR), but the underlying molecular mechanisms are not completely understood. Here, we aimed to investigate the effects and molecular regulation of HIF-1a on brain cell apoptosis and autophagy during IR....

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Detalles Bibliográficos
Autor principal: Guo, Yongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716744/
https://www.ncbi.nlm.nih.gov/pubmed/29228704
http://dx.doi.org/10.18632/oncotarget.21445