YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways

The Hippo pathway is an evolutionarily conserved signaling pathway that regulates proliferation and apoptosis to control organ size during developmental growth. Yes-associated protein 1 (YAP1), the terminal effector of the Hippo pathway, is a transcriptional co-activator and a potent growth promoter...

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Detalles Bibliográficos
Autores principales: Andrade, Daniel, Mehta, Meghna, Griffith, James, Panneerselvam, Janani, Srivastava, Akhil, Kim, Tae-Dong, Janknecht, Ralf, Herman, Terence, Ramesh, Rajagopal, Munshi, Anupama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716745/
https://www.ncbi.nlm.nih.gov/pubmed/29228705
http://dx.doi.org/10.18632/oncotarget.21913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716745/
https://www.ncbi.nlm.nih.gov/pubmed/29228705
http://dx.doi.org/10.18632/oncotarget.21913

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