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Targeting LncRNA HOTAIR suppresses cancer stemness and metastasis in oral carcinomas stem cells through modulation of EMT

Increasing evidence indicates that long non-coding RNAs (lncRNAs) regulate diverse cellular processes, such as cell growth, apoptosis and tumorigenesis. However, the functional roles of lncRNAs and mechanistic analysis of their interplays with oncogenic pathways in oral cancer remain largely unknown...

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Detalles Bibliográficos
Autores principales: Lu, Ming-Yi, Liao, Yi-Wen, Chen, Pei-Yin, Hsieh, Pei-Ling, Fang, Chih-Yuan, Wu, Chia-Yu, Yen, Ming-Liang, Peng, Bou-Yue, Wang, Dayen Peter, Cheng, Hsin-Chung, Wu, Ching-Zong, Shih, Yung-Hsun, Wang, Duen-Jeng, Yu, Cheng-Chia, Tsai, Lo-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716749/
https://www.ncbi.nlm.nih.gov/pubmed/29228709
http://dx.doi.org/10.18632/oncotarget.21614