Sox2 modulates motility and enhances progression of colorectal cancer via the Rho-ROCK signaling pathway

Sox2 (Sry-box2) is essential for a variety of stem cells and is also expressed in colorectal cancer (CRC). However, the underlying mechanism by which Sox2 enhances CRC progression remains unclear. In the present study, we show that elevated Sox2 expression is significantly correlated with poor clini...

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Detalles Bibliográficos
Autores principales: Zheng, Junheng, Xu, Lixiao, Pan, Yubin, Yu, Shuyi, Wang, Hongbo, Kennedy, Derek, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716756/
https://www.ncbi.nlm.nih.gov/pubmed/29228716
http://dx.doi.org/10.18632/oncotarget.21709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716756/
https://www.ncbi.nlm.nih.gov/pubmed/29228716
http://dx.doi.org/10.18632/oncotarget.21709

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