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Sox2 modulates motility and enhances progression of colorectal cancer via the Rho-ROCK signaling pathway
Sox2 (Sry-box2) is essential for a variety of stem cells and is also expressed in colorectal cancer (CRC). However, the underlying mechanism by which Sox2 enhances CRC progression remains unclear. In the present study, we show that elevated Sox2 expression is significantly correlated with poor clini...
Autores principales: | Zheng, Junheng, Xu, Lixiao, Pan, Yubin, Yu, Shuyi, Wang, Hongbo, Kennedy, Derek, Zhang, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716756/ https://www.ncbi.nlm.nih.gov/pubmed/29228716 http://dx.doi.org/10.18632/oncotarget.21709 |
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