Cargando…

Increased single-strand annealing rather than non-homologous end-joining predicts hereditary ovarian carcinoma

Mutations in genes encoding DNA double-strand break (DSB) repair components, especially homologous recombination (HR) proteins, were found to predispose to breast and ovarian cancer. Beyond high penetrance risk gene mutations underlying monogenic defects, low risk gene mutations generate polygenic d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deniz, Miriam, Romashova, Tatiana, Kostezka, Sarah, Faul, Anke, Gundelach, Theresa, Moreno-Villanueva, Maria, Janni, Wolfgang, Friedl, Thomas W.P., Wiesmüller, Lisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716758/ https://www.ncbi.nlm.nih.gov/pubmed/29228718 http://dx.doi.org/10.18632/oncotarget.21720

Ejemplares similares

Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks
por: van de Kooij, Bert, et al.
Publicado: (2022)

Hierarchy of nonhomologous end-joining, single-strand annealing and gene conversion at site-directed DNA double-strand breaks
por: Mansour, Wael Y., et al.
Publicado: (2008)

Non-Homologous End Joining and Homology Directed DNA Repair Frequency of Double-Stranded Breaks Introduced by Genome Editing Reagents
por: Zaboikin, Michail, et al.
Publicado: (2017)

CRISPR-based gene editing of non-homologous end joining factors biases DNA repair pathway choice toward single-strand annealing in Aedes aegypti
por: Chae, Keun, et al.
Publicado: (2023)

Sex-specific differences in DNA double-strand break repair of cycling human lymphocytes during aging
por: Rall-Scharpf, Melanie, et al.
Publicado: (2021)

A Single-Strand Annealing Protein Clamps DNA to Detect and Secure Homology
por: Ander, Marcel, et al.
Publicado: (2015)

ZEB1 promotes non-homologous end joining double-strand break repair
por: Genetta, Thomas L, et al.
Publicado: (2023)

53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients
por: Schochter, Fabienne, et al.
Publicado: (2020)

One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks
por: Ensminger, Michael, et al.
Publicado: (2020)

Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin
por: Manova, Vasilissa, et al.
Publicado: (2012)

The Efficiency of Homologous Recombination and Non-Homologous End Joining Systems in Repairing Double-Strand Breaks during Cell Cycle Progression
por: Bee, Leonardo, et al.
Publicado: (2013)

Single-Strand Annealing in Cancer
por: Blasiak, Janusz
Publicado: (2021)

Inhibition of double-strand break non-homologous end-joining by cisplatin adducts in human cell extracts
por: Diggle, C. P., et al.
Publicado: (2005)

A pathway for error-free non-homologous end joining of resected meiotic double-strand breaks
por: Hatkevich, Talia, et al.
Publicado: (2021)

Either Non-Homologous Ends Joining or Homologous Recombination Is Required to Repair Double-Strand Breaks in the Genome of Macrophage-Internalized Mycobacterium tuberculosis
por: Brzostek, Anna, et al.
Publicado: (2014)

Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes
por: Chakraborty, Anirban, et al.
Publicado: (2016)

Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joining
por: Liang, Zhuobin, et al.
Publicado: (2016)

Double Strand Break DNA Repair occurs via Non-Homologous End-Joining in Mouse MII Oocytes
por: Martin, Jacinta H., et al.
Publicado: (2018)

Inhibiting DNA-PKcs in a non-homologous end-joining pathway in response to DNA double-strand breaks
por: Dong, Jun, et al.
Publicado: (2017)

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination
por: Chitnis, Meenali M., et al.
Publicado: (2013)

Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining
por: Cullati, Sierra N., et al.
Publicado: (2023)

Subdiffusion Supports Joining Of Correct Ends During Repair Of DNA Double-Strand Breaks
por: Girst, S., et al.
Publicado: (2013)

Synthesis-Dependent Strand Annealing in Meiosis
por: McMahill, Melissa S, et al.
Publicado: (2007)

The spatial organization of non-homologous end joining: From bridging to end joining
por: Ochi, Takashi, et al.
Publicado: (2014)

DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination
por: Biehs, Ronja, et al.
Publicado: (2017)

The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF
por: Jessulat, Matthew, et al.
Publicado: (2021)

DNA strand displacement, strand annealing and strand swapping by the Drosophila Bloom's syndrome helicase
por: Weinert, Brian T., et al.
Publicado: (2007)

Msh2 Blocks an Alternative Mechanism for Non-Homologous Tail Removal during Single-Strand Annealing in Saccharomyces cerevisiae
por: Manthey, Glenn M., et al.
Publicado: (2009)

A SRS2 homolog from Arabidopsis thaliana disrupts recombinogenic DNA intermediates and facilitates single strand annealing
por: Blanck, Sandra, et al.
Publicado: (2009)

Ku Regulates the Non-Homologous End Joining Pathway Choice of DNA Double-Strand Break Repair in Human Somatic Cells
por: Fattah, Farjana, et al.
Publicado: (2010)

CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1
por: Quennet, Verena, et al.
Publicado: (2011)

Druggable binding sites in the multicomponent assemblies that characterise DNA double-strand-break repair through non-homologous end joining
por: Kefala Stavridi, Antonia, et al.
Publicado: (2020)

DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
por: Head, PamelaSara E, et al.
Publicado: (2023)

Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V(D)J joining
Publicado: (1993)

Strand asymmetry influences mismatch resolution during a single-strand annealing
por: Pokusaeva, Victoria O., et al.
Publicado: (2022)

Extensive ssDNA end formation at DNA double-strand breaks in non-homologous end-joining deficient cells during the S phase
por: Karlsson, Karin H, et al.
Publicado: (2007)

Polymerase μ in non-homologous DNA end joining: importance of the order of arrival at a double-strand break in a purified system
por: Zhao, Bailin, et al.
Publicado: (2020)

The N-Myc-responsive lncRNA MILIP promotes DNA double-strand break repair through non-homologous end joining
por: Wang, Pei Lin, et al.
Publicado: (2022)

Correction to ‘DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining’
Publicado: (2023)

Proximal binding of dCas9 at a DNA double strand break stimulates homology-directed repair as a local inhibitor of classical non-homologous end joining
por: Feng, Yi-Li, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0qi173tmtfg08i80lcpje46nk7