Routine Use of Clinical Exome-Based Next Generation Sequencing for Evaluation of Patients with Thrombotic Microangiopathies

Next-generation sequencing is increasingly used for clinical evaluation of patients presenting with thrombotic microangiopathies because it allows for simultaneous interrogation of multiple complement and coagulation pathway genes known to be associated with disease. However, the diagnostic yield is...

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Detalles Bibliográficos
Autores principales: Gaut, Joseph P., Jain, Sanjay, Pfeifer, John D., Vigh-Conrad, Katinka A., Corliss, Meagan, Sharma, Mukesh K., Heusel, Jonathan W., Cottrell, Catherine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716882/
https://www.ncbi.nlm.nih.gov/pubmed/28752844
http://dx.doi.org/10.1038/modpathol.2017.90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716882/
https://www.ncbi.nlm.nih.gov/pubmed/28752844
http://dx.doi.org/10.1038/modpathol.2017.90

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