[(18)F]-BMS-747158-02PET imaging for evaluating hepatic mitochondrial complex 1dysfunction in a mouse model of non-alcoholic fatty liver disease

BACKGROUND: Mitochondrial dysfunction is one of the main causes of non-alcohol fatty liver disease (NAFLD). [(18)F]-BMS-747158-02 ((18)F-BMS) which was originally developed as a myocardial perfusion imaging agent was reported to bind mitochondrial complex-1 (MC-1). The aim of this study was to inves...

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Detalles Bibliográficos
Autores principales: Rokugawa, Takemi, Momosaki, Sotaro, Ito, Miwa, Iimori, Hitoshi, Kato, Yuki, Abe, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716959/
https://www.ncbi.nlm.nih.gov/pubmed/29209997
http://dx.doi.org/10.1186/s13550-017-0345-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716959/
https://www.ncbi.nlm.nih.gov/pubmed/29209997
http://dx.doi.org/10.1186/s13550-017-0345-5

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