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Inhibition of A(2A) Adenosine Receptor Signaling in Cancer Cells Proliferation by the Novel Antagonist TP455

Several evidences indicate that the ubiquitous nucleoside adenosine, acting through A(1), A(2A), A(2B), and A(3) receptor (AR) subtypes, plays crucial roles in tumor development. Adenosine has contrasting effects on cell proliferation depending on the engagement of different receptor subtypes in var...

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Detalles Bibliográficos
Autores principales: Gessi, Stefania, Bencivenni, Serena, Battistello, Enrica, Vincenzi, Fabrizio, Colotta, Vittoria, Catarzi, Daniela, Varano, Flavia, Merighi, Stefania, Borea, Pier Andrea, Varani, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716981/
https://www.ncbi.nlm.nih.gov/pubmed/29249971
http://dx.doi.org/10.3389/fphar.2017.00888