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Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer

Epithelial-to-mesenchymal transition (EMT) allows epithelial cancer cells to assume mesenchymal features, endowing them with enhanced motility and invasiveness, thus enabling cancer dissemination and metastatic spread. The induction of EMT is orchestrated by EMT-inducing transcription factors that s...

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Detalles Bibliográficos
Autores principales: Guerra, Flora, Guaragnella, Nicoletta, Arbini, Arnaldo A., Bucci, Cecilia, Giannattasio, Sergio, Moro, Loredana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716985/
https://www.ncbi.nlm.nih.gov/pubmed/29250487
http://dx.doi.org/10.3389/fonc.2017.00295