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Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer
Epithelial-to-mesenchymal transition (EMT) allows epithelial cancer cells to assume mesenchymal features, endowing them with enhanced motility and invasiveness, thus enabling cancer dissemination and metastatic spread. The induction of EMT is orchestrated by EMT-inducing transcription factors that s...
Autores principales: | Guerra, Flora, Guaragnella, Nicoletta, Arbini, Arnaldo A., Bucci, Cecilia, Giannattasio, Sergio, Moro, Loredana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716985/ https://www.ncbi.nlm.nih.gov/pubmed/29250487 http://dx.doi.org/10.3389/fonc.2017.00295 |
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