Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link

Diabetic insulin resistance and pro-diabetic diet are reported to increase dementia risk through unknown mechanisms. Emerging evidence suggests that the integrity of blood-brain barrier (BBB) is central to the onset and progression of neurodegeneration and cognitive impairment. Therefore, the curren...

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Detalles Bibliográficos
Autores principales: Takechi, Ryusuke, Lam, Virginie, Brook, Emily, Giles, Corey, Fimognari, Nicholas, Mooranian, Armin, Al-Salami, Hani, Coulson, Stephanie H., Nesbit, Michael, Mamo, John C. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717019/
https://www.ncbi.nlm.nih.gov/pubmed/29249964
http://dx.doi.org/10.3389/fnagi.2017.00399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717019/
https://www.ncbi.nlm.nih.gov/pubmed/29249964
http://dx.doi.org/10.3389/fnagi.2017.00399

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