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Blood-Brain Barrier Dysfunction Precedes Cognitive Decline and Neurodegeneration in Diabetic Insulin Resistant Mouse Model: An Implication for Causal Link

Diabetic insulin resistance and pro-diabetic diet are reported to increase dementia risk through unknown mechanisms. Emerging evidence suggests that the integrity of blood-brain barrier (BBB) is central to the onset and progression of neurodegeneration and cognitive impairment. Therefore, the curren...

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Detalles Bibliográficos
Autores principales:	Takechi, Ryusuke, Lam, Virginie, Brook, Emily, Giles, Corey, Fimognari, Nicholas, Mooranian, Armin, Al-Salami, Hani, Coulson, Stephanie H., Nesbit, Michael, Mamo, John C. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717019/ https://www.ncbi.nlm.nih.gov/pubmed/29249964 http://dx.doi.org/10.3389/fnagi.2017.00399

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