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Establishment of a strain of haemophilia-A pigs by xenografting of foetal testicular tissue from neonatally moribund cloned pigs

Grafting of testicular tissue into immunodeficient mice makes it possible to obtain functional sperm from immature donor animals that cannot be used for reproduction. We have developed a porcine model of human haemophilia A (haemophilia-A pigs) by nuclear transfer cloning from foetal fibroblasts aft...

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Detalles Bibliográficos
Autores principales: Kaneko, Hiroyuki, Kikuchi, Kazuhiro, Nakai, Michiko, Fuchimoto, Daiichiro, Suzuki, Shunichi, Sembon, Shoichiro, Noguchi, Junko, Onishi, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717049/
https://www.ncbi.nlm.nih.gov/pubmed/29208927
http://dx.doi.org/10.1038/s41598-017-17017-6