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Establishment of a strain of haemophilia-A pigs by xenografting of foetal testicular tissue from neonatally moribund cloned pigs
Grafting of testicular tissue into immunodeficient mice makes it possible to obtain functional sperm from immature donor animals that cannot be used for reproduction. We have developed a porcine model of human haemophilia A (haemophilia-A pigs) by nuclear transfer cloning from foetal fibroblasts aft...
Autores principales: | Kaneko, Hiroyuki, Kikuchi, Kazuhiro, Nakai, Michiko, Fuchimoto, Daiichiro, Suzuki, Shunichi, Sembon, Shoichiro, Noguchi, Junko, Onishi, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717049/ https://www.ncbi.nlm.nih.gov/pubmed/29208927 http://dx.doi.org/10.1038/s41598-017-17017-6 |
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