Repurposing an inhibitor of ribosomal biogenesis with broad anti-fungal activity

The lack of new antifungal compounds with unique mechanisms of action is a concern for therapeutic management of patients. To identify inhibitors against human pathogenic fungi, we screened ~3000 compounds provided by the Developmental Therapeutics Program of NIH/NCI against a panel of pathogenic fu...

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Detalles Bibliográficos
Autores principales: Sun, Nuo, Li, Dongmei, Zhang, Yuhan, Killeen, Kyle, Groutas, William, Calderone, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717060/
https://www.ncbi.nlm.nih.gov/pubmed/29209049
http://dx.doi.org/10.1038/s41598-017-17147-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717060/
https://www.ncbi.nlm.nih.gov/pubmed/29209049
http://dx.doi.org/10.1038/s41598-017-17147-x

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