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HSP60 possesses a GTPase activity and mediates protein folding with HSP10

The mammalian molecular chaperone, HSP60, plays an essential role in protein homeostasis through mediating protein folding and assembly. The structure and ATP-dependent function of HSP60 has been well established in recent studies. After ATP, GTP is the major cellular nucleotide. In this paper, we h...

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Detalles Bibliográficos
Autores principales: Okamoto, Tomoya, Yamamoto, Hiroshi, Kudo, Ikuru, Matsumoto, Kazuya, Odaka, Masafumi, Grave, Ewa, Itoh, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717063/
https://www.ncbi.nlm.nih.gov/pubmed/29208924
http://dx.doi.org/10.1038/s41598-017-17167-7