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Alternative substrate-bound conformation of bacterial solute-binding protein involved in the import of mammalian host glycosaminoglycans

Glycosaminoglycans (GAGs), constituted by repeating uronate and amino sugar units, are major components of mammalian extracellular matrices. Some indigenous and pathogenic bacteria target GAGs for colonization to and/or infection of host mammalian cells. In Gram-negative pathogenic Streptobacillus m...

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Detalles Bibliográficos
Autores principales: Oiki, Sayoko, Kamochi, Reiko, Mikami, Bunzo, Murata, Kousaku, Hashimoto, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717064/
https://www.ncbi.nlm.nih.gov/pubmed/29208901
http://dx.doi.org/10.1038/s41598-017-16801-8