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Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis

Autophagy is a pathophysiological phenomenon in liver cirrhosis that can further progress into hepatocarcinoma. Liver cancer stem cells (CSCs) are believed to initiate hepatocarcinogenesis. To investigate the precise mechanism related to the origin of CSCs in liver cirrhosis and hepatocarcinogenesis...

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Detalles Bibliográficos
Autores principales: Li, J, Hu, S B, Wang, L Y, Zhang, X, Zhou, X, Yang, B, Li, J H, Xiong, J, Liu, N, Li, Y, Wu, Y Z, Zheng, Q C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717078/
https://www.ncbi.nlm.nih.gov/pubmed/28783177
http://dx.doi.org/10.1038/onc.2017.272