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Autophagy-dependent generation of Axin2+ cancer stem-like cells promotes hepatocarcinogenesis in liver cirrhosis
Autophagy is a pathophysiological phenomenon in liver cirrhosis that can further progress into hepatocarcinoma. Liver cancer stem cells (CSCs) are believed to initiate hepatocarcinogenesis. To investigate the precise mechanism related to the origin of CSCs in liver cirrhosis and hepatocarcinogenesis...
Autores principales: | Li, J, Hu, S B, Wang, L Y, Zhang, X, Zhou, X, Yang, B, Li, J H, Xiong, J, Liu, N, Li, Y, Wu, Y Z, Zheng, Q C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717078/ https://www.ncbi.nlm.nih.gov/pubmed/28783177 http://dx.doi.org/10.1038/onc.2017.272 |
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