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Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway

Autophagy is a physiological process, important for recycling of macromolecules and maintenance of cellular homeostasis. Defective autophagy is associated with tumorigenesis and has a causative role in chemotherapy resistance in leukemia and in solid cancers. Here, we report that autophagy is regula...

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Detalles Bibliográficos
Autores principales: Ambrosio, S, Saccà, C D, Amente, S, Paladino, S, Lania, L, Majello, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717079/
https://www.ncbi.nlm.nih.gov/pubmed/28783174
http://dx.doi.org/10.1038/onc.2017.267