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Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway
Autophagy is a physiological process, important for recycling of macromolecules and maintenance of cellular homeostasis. Defective autophagy is associated with tumorigenesis and has a causative role in chemotherapy resistance in leukemia and in solid cancers. Here, we report that autophagy is regula...
Autores principales: | Ambrosio, S, Saccà, C D, Amente, S, Paladino, S, Lania, L, Majello, B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717079/ https://www.ncbi.nlm.nih.gov/pubmed/28783174 http://dx.doi.org/10.1038/onc.2017.267 |
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