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Possible function of the second RecJ-like protein in stalled replication fork repair by interacting with Hef

RecJ was originally identified in Escherichia coli and plays an important role in the DNA repair and recombination pathways. Thermococcus kodakarensis, a hyperthermophilic archaeon, has two RecJ-like nucleases. These proteins are designated as GAN (GINS-associated nuclease) and HAN (Hef-associated n...

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Detalles Bibliográficos
Autores principales: Nagata, Mariko, Ishino, Sonoko, Yamagami, Takeshi, Simons, Jan-Robert, Kanai, Tamotsu, Atomi, Haruyuki, Ishino, Yoshizumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717133/
https://www.ncbi.nlm.nih.gov/pubmed/29209094
http://dx.doi.org/10.1038/s41598-017-17306-0