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Enhanced CD25(+)Foxp3(+) regulatory T cell development by amodiaquine through activation of nuclear receptor 4A
CD4(+) T cells play key roles in the regulation of immune responses against pathogenic infectious antigens via development into effector T helper and induced regulatory T (iTreg) cells. Particularly, CD4(+)CD25(+)Foxp3(+) iTreg cells are crucial for maintaining immune homeostasis and controlling inf...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717225/ https://www.ncbi.nlm.nih.gov/pubmed/29208963 http://dx.doi.org/10.1038/s41598-017-17073-y |