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Enhanced CD25(+)Foxp3(+) regulatory T cell development by amodiaquine through activation of nuclear receptor 4A

CD4(+) T cells play key roles in the regulation of immune responses against pathogenic infectious antigens via development into effector T helper and induced regulatory T (iTreg) cells. Particularly, CD4(+)CD25(+)Foxp3(+) iTreg cells are crucial for maintaining immune homeostasis and controlling inf...

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Detalles Bibliográficos
Autores principales: Won, Hee Yeon, Shin, Ji Hyun, Oh, Sera, Jeong, Hana, Hwang, Eun Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717225/
https://www.ncbi.nlm.nih.gov/pubmed/29208963
http://dx.doi.org/10.1038/s41598-017-17073-y