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Network dynamics-based cancer panel stratification for systemic prediction of anticancer drug response
Cancer is a complex disease involving multiple genomic alterations that disrupt the dynamic response of signaling networks. The heterogeneous nature of cancer, which results in highly variable drug response, is a major obstacle to developing effective cancer therapy. Previous studies of cancer thera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717260/ https://www.ncbi.nlm.nih.gov/pubmed/29208897 http://dx.doi.org/10.1038/s41467-017-02160-5 |