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Statistical methods to detect pleiotropy in human complex traits

In recent years pleiotropy, the phenomenon of one genetic locus influencing several traits, has become a widely researched field in human genetics. With the increasing availability of genome-wide association study summary statistics, as well as the establishment of deeply phenotyped sample collectio...

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Detalles Bibliográficos
Autores principales: Hackinger, Sophie, Zeggini, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717338/
https://www.ncbi.nlm.nih.gov/pubmed/29093210
http://dx.doi.org/10.1098/rsob.170125