The human CTF4-orthologue AND-1 interacts with DNA polymerase α/primase via its unique C-terminal HMG box

A dynamic multi-protein assembly known as the replisome is responsible for DNA synthesis in eukaryotic cells. In yeast, the hub protein Ctf4 bridges DNA helicase and DNA polymerase and recruits factors with roles in metabolic processes coupled to DNA replication. An important question in DNA replica...

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Detalles Bibliográficos
Autores principales: Kilkenny, Mairi L., Simon, Aline C., Mainwaring, Jack, Wirthensohn, David, Holzer, Sandro, Pellegrini, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717350/
https://www.ncbi.nlm.nih.gov/pubmed/29167311
http://dx.doi.org/10.1098/rsob.170217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717350/
https://www.ncbi.nlm.nih.gov/pubmed/29167311
http://dx.doi.org/10.1098/rsob.170217

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