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Severity of Acute Infectious Mononucleosis Correlates with Cross-Reactive Influenza CD8 T-Cell Receptor Repertoires

Fifty years after the discovery of Epstein-Barr virus (EBV), it remains unclear how primary infection with this virus leads to massive CD8 T-cell expansion and acute infectious mononucleosis (AIM) in young adults. AIM can vary greatly in severity, from a mild transient influenza-like illness to a pr...

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Detalles Bibliográficos
Autores principales: Aslan, Nuray, Watkin, Levi B., Gil, Anna, Mishra, Rabinarayan, Clark, Fransenio G., Welsh, Raymond M., Ghersi, Dario, Luzuriaga, Katherine, Selin, Liisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717389/
https://www.ncbi.nlm.nih.gov/pubmed/29208744
http://dx.doi.org/10.1128/mBio.01841-17