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Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation

Candida albicans remains the main etiologic agent of candidiasis, the most common fungal infection and now the third most frequent infection in U.S. hospitals. The scarcity of antifungal agents and their limited efficacy contribute to the unacceptably high morbidity and mortality rates associated wi...

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Detalles Bibliográficos
Autores principales: Romo, Jesus A., Pierce, Christopher G., Chaturvedi, Ashok K., Lazzell, Anna L., McHardy, Stanton F., Saville, Stephen P., Lopez-Ribot, Jose L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717394/
https://www.ncbi.nlm.nih.gov/pubmed/29208749
http://dx.doi.org/10.1128/mBio.01991-17