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Study on orally delivered paclitaxel nanocrystals: modification, characterization and activity in the gastrointestinal tract
Drug nanocrystals (NCs) can improve the solubility and bioavailability of insoluble drugs for oral administration. However, the biocompatibility and mechanisms of transmittance of drug NCs through the intestinal epithelial tissue are still not well understood. In this work, the physico-chemical prop...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society Publishing
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717641/ https://www.ncbi.nlm.nih.gov/pubmed/29291067 http://dx.doi.org/10.1098/rsos.170753 |