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An efficient synthesis of 4H-pyrano quinolinone derivatives catalysed by a versatile organocatalyst tetra-n-butylammonium fluoride and their pharmacological screening

A new series of indole-based pyranoquinoline derivatives P(1–24) has been synthesized by a one-pot cyclocondensation reaction of 2-(4-substituted)phenyl-N-allyl-indole-3-carbaldehydes 1a–d; active methylenes 2a–c; and 4-hydroxy-1-substituted quinolin-2(1H)-one 3a–b catalysed by an organocatalyst tet...

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Detalles Bibliográficos
Autores principales: Prasad, Pratibha, Shobhashana, Pratik G., Patel, Manish P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717643/
https://www.ncbi.nlm.nih.gov/pubmed/29291069
http://dx.doi.org/10.1098/rsos.170764