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Methylation mediated Gadd45β enhanced the chemosensitivity of hepatocellular carcinoma by inhibiting the stemness of liver cancer cells

BACKGROUND: Defects of the growth arrest DNA damage-inducible gene 45β (Gadd45β) play an important role in the progression of tumor and confer resistance to chemotherapy. However, the role of Gadd45β in the apoptosis of hepatocellular carcinoma is still not clear. Purpose of this study was to explor...

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Detalles Bibliográficos
Autores principales: Hou, Xiao-Juan, Zhao, Qiu-Dong, Jing, Ying-Ying, Han, Zhi-Peng, Yang, Xue, Wei, Li-Xin, Zheng, Yu-Ting, Xie, Feng, Zhang, Bai-He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717842/
https://www.ncbi.nlm.nih.gov/pubmed/29225771
http://dx.doi.org/10.1186/s13578-017-0189-8