Human mitochondrial MTHFD2 is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase

BACKGROUND: Folate-dependent one-carbon metabolism provides one-carbon units for several biological processes. This pathway is highly compartmentalized in eukaryotes, with the mitochondrial pathway producing formate for use in cytoplasmic processes. The mitochondrial enzyme MTHFD2 has been reported...

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Detalles Bibliográficos
Autores principales: Shin, Minhye, Momb, Jessica, Appling, Dean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718140/
https://www.ncbi.nlm.nih.gov/pubmed/29225823
http://dx.doi.org/10.1186/s40170-017-0173-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718140/
https://www.ncbi.nlm.nih.gov/pubmed/29225823
http://dx.doi.org/10.1186/s40170-017-0173-0

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