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The optimal design of stepped wedge trials with equal allocation to sequences and a comparison to other trial designs

BACKGROUND/AIMS: We sought to optimise the design of stepped wedge trials with an equal allocation of clusters to sequences and explored sample size comparisons with alternative trial designs. METHODS: We developed a new expression for the design effect for a stepped wedge trial, assuming that obser...

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Detalles Bibliográficos
Autores principales: Thompson, Jennifer A, Fielding, Katherine, Hargreaves, James, Copas, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718336/
https://www.ncbi.nlm.nih.gov/pubmed/28797179
http://dx.doi.org/10.1177/1740774517723921