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Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway

Resveratrol (RSV), a natural polyphenol, has been reported to produce effect on genes transcription in lipid metabolism. In this study, we aim to explore the novel mechanisms of RSV on the regulation of caveolin-1 (Cav-1) transcription. Via body weight, blood glucose, serum lipid, and liver patholog...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Chen, Qiuxia, Sun, Fangyun, Zhao, Nana, Wen, Lirong, Li, Lin, Ran, Gai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718516/
https://www.ncbi.nlm.nih.gov/pubmed/29211809
http://dx.doi.org/10.1371/journal.pone.0189156